
The service which will take place this Sunday at St Nicholas church is held every year in the same month that HMS Tigris sank with all 63 crew on board.
The memorial event attracts up to 100 people a year, including relatives of the 63 crew members.
Newbury adopted the Tigris as part of a national scheme.
Towns all over the UK adopted ships and submarines to raise money for the Navy during World War II.